This presentation will discuss the potential of biodegradable star polymers as drug delivery vehicles. Well-defined, multi-armed star polymers have been prepared by either �arm first� or �core first� synthetic approaches.  Strategies to introduce core and/or peripheral functionality in core-shell star polymers have been taken to tune the properties of the carriers. Multi-armed star polymers demonstrated the ability to spontaneously form occlusion complexes with variety of bioactive molecules. The degradation of these complexes under physiological conditions makes star-polymers attractive candidates for drug delivery.

Biodegradable nanogel star polymers: A platform for programmable macromolecular self-assembly, intercellular transport, and cargo delivery

248th National Meeting (2014)

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