As part of a retrospective screening campaign from our legacy compounds collection to identify new chemical starting points for insecticidal lead discovery programs, we identified benzoxazepine compounds of the general type shown below as a new insecticidal chemical class with potent foliar lab and field activity against sucking insects, such as aphids, whiteflies and scales. Aspects of the synthesis, physico-chemical properties, biology, and structure-activity relationships will be presented. Figure 1. <img src='https://acs-archive-assets2.s3.amazonaws.com/241nm/uploads/62266_rsj2.jpg' alt='' />

Synthesis and insecticidal activity of new 2-aryl-3,5-dihydro-2H-1,4-benzoxazepine derivatives

248th National Meeting (2014)

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