Oxathiapiprolin, DuPont� Zorvec� is a reduced-risk fungicide rated as excellent or equivalent to the best in class for most oomycete diseases with a novel mode of action. Oxathiapiprolin metabolized in hen, goat, rat, and plants primarily through hydroxylation and further oxidation reactions. The cleavage of the bond between the piperidine ring nitrogen and the pyrazole nitrogen resulting in pyrazole moiety metabolites was also a significant metabolic route of dissipation. Hydroxylation in the isoxazoline ring followed by dehydration resulted in a non-polar metabolite in animals and plants. Approximately 20 metabolites were identified in animals and plants. In general, the metabolic reactions in animals and plants were consistent.

Metabolic pathways of DuPont� Zorvec� (oxathiapiprolin) in animals and plants for identifying residues included in dietary risk assessments

248th National Meeting (2014)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.