Biofilms are made of communities of microbial cells that grow on living or inert surfaces. The formation of biofilms presents a fundamental problem in water technology, environmental biology, food hygiene and in many medical and technical systems. It is therefore necessary to investigate methods to prevent the growth of biofilms. This study will examine the inhibition of the growth of Pseudomonas Aureginosa on a glass slide by modifying a glass surface using hydrophobic liquid-infused nano-porous poly(butyl methacrylate-co-ethylene dimethacrylate) polymers (slippery BMA-EDMA). As a mimic to bacterial adhesion, Texas red-conjugated BSA will be adsorbed to plain; liquid-infused and non-liquid-infused nano-porous polymer covered glass surfaces. Analysis of simulated samples using fluorescence microscopy showed that BSA adhered at a higher level to the plain glass surface than to the polymer coated glass surface. Studies are underway to determine if the novel surfaces prevent adhesion of biofilms generated by Pseudomonas Aeruginosa.

Preparation of antibacterial surfaces by liquid-infused nanoporous polymer

249th National Meeting (2015)

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