Ten weeks of research in Germany culminated in vast scientific and personal growth. During a summer internship at the University of Jena, the total organic synthesis of (+) and (–) parthenolide was researched. The natural product (–)-parthenolide has much potential as an anti-cancer therapeutic due to its ability to selectively induce apoptosis in cancer stem cells, effectively killing cancer “at the root of the cause” while leaving healthy cells intact. Here we discuss a synthetic approach for (+)- and (–)-Parthenolide to further analyze the pharmacological properties of the naturally occurring parthenolide and its unknown enantiomer. My IREU experience resulted in international collaboration and scientific cross-cultural communication. In addition, I learned how to expand personal boundaries and learn about different cultures.

Undergraduate research in Jena: Scientific and personal discovery in Germany

251st National Meeting (2016)

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