The concept of active template in the copper mediated synthesis of rotaxanes has been developed in the last few years and its possible iterative character was demonstrated very recently.<br/>The recent extension of the concept to a “double active template” will be presented. The ditopic nature of the strapped porphyrin ligand led to heterobimetallic Zn-Cu complexes that have been used in copper-induced cycloaddition reactions (see Figure).<br/>Taking advantage of the coordinating character of the azide group and it was demonstrated that the zinc(II) in the porphyrin core is essential to the synthesis of the rotaxane structure with good to excellent yields. In the absence of the zinc(II) (e.g. replacement with Ni<sup>II</sup>), no rotaxane was obtained. Application of this synthetic strategy to functional rotaxanes will also be discussed.

Double active template strategy for functional rotaxane synthesis

253rd National Meeting (2017)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.