The risk of exposure to single or mixture toxicity is seldom assessed considering the factors of physical environment except temperature, atmospheric pressure, humidity, potentially over- or underestimating biological and ecological effects on ecosystems. Varying magnetic field has impacts on the biological organism. Recent findings indicate that the weak magnetic field (WMF) can enhance the removal ability of target pollutants in the water. Some protein expressions are indeed influenced by magnetic fields in biological organism. Hormesis is that “exposure to a low dose of a chemical that is damaging at higher doses, induces an adaptive upgrade of cellular protection”. The process of hormesis can be illustrated with the ubiquitous environmental pollutant antibiotics. In other research, we found that polymyxin B sulfate (POL) can induce hormesis at 9h and 12h in the experiments of the time-dependent toxicity. This phenomenon propels us to investigate whether WMF can give a rise to the hormetic response or not. Four experimental groups were set up, i.e. all the time with WMF (T1), all the time without WMF (T2), with WMF only during the bacterial culture (T3) and with WMF only in toxicity test (T4). The toxicity test to <i>Vibrio qinghaiensis</i> at five time points such as 0.25, 3, 6, 9 and 12 h were determined by the time-dependent microplate toxicity analysis (t-MTA). All types of toxicity test can induce hormesis at 9h and 12h. T3 and T4 can induce hormesis earlier, at 6h. Interestingly, the hormesis effects enhanced by weak magnetic field did not occur in T1. WMF can increase the degree of hormesis in T3 and T4. These findings indicate that the weak magnetic field can enhance hormesis effect in time-dependent toxicity test of POL.

Effect of hormesis of polymyxin B sulfate enhanced by weak magnetic field on <i>Vibrio qinghaiensis</i> sp.-Q67

254th National Meeting (2017)

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Effect of hormesis of polymyxin B sulfate enhanced by weak magnetic field on Vibrio qinghaiensis sp.-Q67