Chili seeds, abandoned in the production of chili powder and chili paste, contain a variety of substances that can lead to useful products. In this paper, the chili seed oil’s antioxidant, bacteriostatic and antitumor acitivities were analysized. 1) IC50 values of antioxidant ability were 2.11 mg/mL in DPPH system and 1.58 mg/mL in β-carotene-linoleic acid oxidation experiment, which both showed that chili seed oil possessed a desirably high activity of antioxidantion. 2) Chili seed oil showed better inhibitory effect on Bacillus subtilis and Shigella flexneri than other bacteria and fungus by evaluating the diameter for inhibitory zone, minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC). Scanning electron microscope (SEM) and transmission electron microscope (TEM) showed that membrane permeability of cells was changed and destroyed after the treatment of chili seed oil, which caused the destruction or depletion of cytoplasm. 3) Crystal violet staining (CVS) method showed a siginicifant inhibitory effect of chili seed oil on Hep G2 and MDA-MB-231 cells (P&lt;0.05) in vitro. IC50 values of inhibiting Hep G2 and MDA-MB-231 cells were 0.291 and 0.328 mg/mL, respectively. All these foundings indicate a good antioxidant, bacteriostatic and antitumor acitivities of chilli seed oil, which could be developed or added to functional foods.

Study on the antioxidant, bacteriostatic and antitumor acitivities of chili seed oil

254th National Meeting (2017)

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