Several chalcone derivatives were prepared through an aldol condensation reaction using para-substituted trans-cinnamaldehyde compounds and para-substituted acetophenones. The reactions yield highly colored solids, and these products can be characterized with IR and UV-VIS. Additionally, 1H, 13C, and 2D NMR spectroscopy will be used to demonstrate the efficacy of such techniques for structural analysis, the effect of different para-substitution groups on the aromatic ring, as well as the cis/trans coupling of the vinylic protons and correlation spectroscopy.

Preparation and NMR analysis of chalcone derivatives

255th National Meeting (2018)

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