The legal landscape for cannabis has changed considerably within the United States and for many other countries.  The US cannabis industry needs a wide range of chromatographic methodologies to fit within the new landscape.  Analytical testing for the different cannabinoids is often the first chromatographic methodology that is developed by company that is new to the industry.  Often this testing is a liquid chromatography application.  Terpenes are another class of compounds that are of interest to the cannabis industry.  Analytical testing for terpenes is often accomplished with gas chromatography.  Pesticide analysis is currently (or soon will be) legally required for commercial cannabis products.  Pesticide testing is often done by gas or liquid chromatography with mass spectrometry. The unique properties of SFC make it a suitable platform for all of these chromatographic methodologies.<br/> <br/>The work presented here will demonstrate SFC-UV and SFC-MS applications for the cannabis industry.  Examples of analytical methodology for purity / potency and identification of common cannabinoids will presented.  SFC applicability for terpene analytical methodology and pesticide analysis will be discussed with cannabinoid related examples being presented. Since SFC is a less common form of chromatography, introductory details of this technique will also be included.

Analytical SFC applications for the cannabis industry

256th National Meeting (2018)

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