A key challenge in nanotechnology is to design and fabricate nanostructures and nanodevices. Such systems can serve as platforms for basic science research (structural biology, molecular biology, for instance) at nanoscale, and for practical applications. Bottom-up structural DNA nanotechnology has attracted significant attentions due to its programmability and its precise control of matter at nanoscale.<br/>This seminar will open with a brief introduction of structural DNA nanotechnology, followed by discussing our recent progress in making massive/complex DNA nanostructures and dynamic DNA devices. Particularly, I will discuss how we can construct fully addressable GDa nanostructures from modular DNA components called “DNA bricks”, and dynamic DNA structure transformation. DNA nanostructures has also shown increasing capabilities for basic science research, and for practical applications, such as fabrication of single-molecule functional nanoscale materials.  I will present our most recent works related to potential drug nanodelivery systems engineered by using DNA self-assembly.

Structural DNA nanotechnology: Complex self-assembly and biomedical applications

256th National Meeting (2018)

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.