Carbohydrate-protein interactions play critical roles in a number of normal biological processes from cell recognition and cell-cell communication to diseased states such as cancer. In this talk, we describe the synthesis of a new class of compounds specifically designed as tools to study the structure/function relationships that govern carbohydrate-protein binding with an emphasis in targeting C-type lectins. In addition to our synthetic work, we will discuss our preliminary biological results using a model C-type lectin, as well potential future applications for our new compounds.

New tools for studying carbohydrate-protein binding interactions

256th National Meeting (2018)

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