The ongoing objective of this project is to develop research techniques and organic synthesis strategies while progressively completing the synthesis of LMA-P2. The overall project is divided into three separate phases of synthesis in which each phase individually focuses on reactions necessary to synthesize precursors for LMA-P2. Each phase revolves around a key synthetic transformation. In order, the phases are as follows: a MacMillan cross-aldol reaction, a Takai olefination reaction, and a Nozaki-Hiyama-Kishi nickel(II) catalyzed coupling reaction. Phase one has been completed with the synthesis of the allylic alcohol from the MacMillan cross-aldol reaction being successful, while phase two and three remain as ongoing endeavors of this research project. This project continues to allow undergraduate researchers to gain valuable experience in chemical transformations, purification techniques, and characterization that is vital for careers that involve synthetic chemistry.

Investigating the synthesis of LMA-P2

2019 Spring National Meeting

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.