This investigation is intended to determine the volatile organic compound responsible for the flavour and biological activities of the root volatile oil of Securidaca longipendiculata. The root volatile oil of S. longipendiculata was obtained by hydrodistillation method using Clevenger type apparatus and analysed by gas chromatography (GC) and gas chromatography coupled with mass spectrometry (GC-MS). The root oil was composed of methyl salicylate (90 %). The antioxidant activity of the root oil was measured using 2,2’-Diphenyl-1-picrylhydrazyl (DPPH) assay. The antibacterial activity of the root oil of S. longipendiculata was carried out using agar well diffusion method. The root oil displayed a good free radical scavenging and antioxidant potentials with IC50 = 6.0 µgml-1. The root oil was tested against multi-drug resistant bacteria: Enterococcus faecalis, Micrococcus varians, Streptococcus agalactiae, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Serratia marcescens and Salmonella typhimurium. The root oil exhibited a strong antibacterial potentials ranging between 20-42 on the growth of bacteria used at varying concentrations. The obtained results showed that the root oil of S. longipendiculata was active as the synthetic antibiotic (gentamicin) used. The high content of methyl salicylate in the root oil could largely be responsible for flavour and biological potentials of the root of the plant.

Chemical composition and biological activities of the root volatile oil of Securidaca longipendiculata fres

2019 Spring National Meeting

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