Numerous diseases can be indicated by the concentration of glutathione present in the body. A self-powered biosensor has been developed to detect glutathione levels in solution. The sensor consists of a glucose oxidase anode and a bilirubin oxidase cathode. For the detection of glutathione present, we utilize the specificity of bilirubin oxidase to show a measurable electrochemical response. The sensor has a detection limit of 410 µM and a linear range from 340 µM to 950 µM. Being able to detect a range of concentrations is essential to diagnosing the severity of diseases, given that the amount glutathione and the disease have some quantifiable correlation. This sensor has the potential to be implemented as a quick, low-cost alternative to previously reported methods.

Self-powered enzymatic biosensor for detection of glutathione

2019 Spring National Meeting

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