Graphene nanomaterials show great versatility with their biocompatibility, affinity for absorbing molecules, and their ability to interact with near-infrared light.  Because of these attributes, these materials show great promise for use in targeted drug delivery and theranostic applications. In this work, the efficacy of a series of functional graphene-gold nanoparticle hybrids are evaluated for use in targeted drug release systems for cancer therapy.  Hybrid graphene oxide nanomaterials conjugated with cancer-specific antibodies were characterized using dynamic light scattering, transmission electron microscopy, and UV-visible, FT-infrared, Raman, and fluorescence spectroscopy.  Kinetic properties of drug release and nanoparticle degradation was evaluated spectroscopically.  The performance of these materials was evaluated in-vitro for binding and destruction of target cancer cells.

Hybrid graphene oxide-gold nanomaterials for targeted cancer theranostics

2019 Spring National Meeting

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