Despite significant progress in the area of membrane protein structure and stability, the role of the lipid environment in stabilizing membrane protein folding, structure, function, and dynamics remains unclear. To begin to understand the interactions between proteins and the solvent environment, the physical properties of the environments used to stabilize membrane protein folds need to be understood. The structure, shape, and dynamics of micelles and bicelles will be presented and compared to membranes. The impact the differences and similarities of these three environments have on membrane proteins will be explored.

Physical properties of membranes and membrane mimics: potential impact on membrane protein structure

2019 Spring National Meeting

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