Chemo- and biosensors based on fluorescent conjugated polymers and oligomers benefit from the greater detection sensitivity due to amplification of the electronic perturbations produced by analyte binding. This amplification stems from the exciton-transporting properties of the conjugated systems. General sensor design paradigms utilize the concept of analyte binding to cause a perturbation of the local energy gap which changes the fluorescent properties of the polymer sensor. In this presentation, recent examples from our laboratory showing development of amplifying fluorescent sensors utilizing various molecular and mesoscale systems will be discussed. These new designs expand the generality and universality of the signal amplification concept in conjugated polymers, and can be used to construct amplifying <i>turn-on</i> and ratiometric fluorescent sensors for various practically useful analytes.

Amplifying fluorescent sensors based on molecular systems with extended electronic delocalization

2019 Spring National Meeting

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.