Contact lenses are widely utilized in today’s society for cosmetic and vision purposes; however, many health problems are caused by surface properties of contact lenses such as poor wettability and protein deposition. This work will utilize chitosan (CS) and hyaluronic acid (HA) multilayers by immersive layer-by-layer (LbL) assembly on siloxy amino functionalized generation 1 and 3 silicone hydrogel contact lenses.   The water retention, protein deposition, and oxygen permeability of the modified contact lenses will be compared to unmodified ones. LbL self-assembled multilayer films have been proven to deliver drugs effectively. The ophthalmic drugs, Timolol and norfloxacin, will be trapped via the LbL assembly process and their release studied.

Immersive layer-by-layer (LbL) assembly on siloxy amino functionalized generation 1 and 3 silicone hydrogel contact lenses

2019 Spring National Meeting

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