The National Toxicology Program (NTP) has a 40-year history of success and public health impact studying some of the most concerning agents in our environment. A lot has changed over that 40 years including the number and diversity of agents we’re exposed to, expectations of our stakeholders and technology. Over a decade ago, our discipline aspired to significantly increase the efficiency with which we could provide insights into putative hazards of novel environmental agents to support our efforts to mitigate those hazards but also to enable industry to develop safe and useful products. We’ve struggled to achieve that in a meaningful and translational way. The NTP is embracing that challenge and invigorating our focus on enhancing our ability to meaningfully translate mechanistic bioactivity to human outcomes. This presentation will provide insights into our strategy, evolution of our portfolio, a translational toxicology pipeline of capabilities and prioritized areas of ‘health effect innovation’.

Embracing translation in toxicology: National toxicology program strategy

2019 Fall National Meeting

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