Various types of transmembrane pores and ion channels in the range of 1-100 nm are found in each biological cell, playing crucial roles in varieties of significant physiological activities such as maintaining cell osmotic balance and stabilizing cell volume. Inspired by this natural phenomenon, different biomimetic nanodevices (nanopore/channel) with different characteristics have emerged as an attractive and powerful platform and have been used for a wide range of applications. Generally, the principle of analysis applications based on solid nanopore/channel can be described as follows: molecules access or attach on the inner surface of a nanopore/channel, change the effective diameter of the nanopore/channel, or affect the charge transfer as well as the wettability of the inner surface of the nanopore/channel, leading to ionic current changes that can be detected.

Analysis and detection based on solid nanopore/channel

ACS Spring Meeting 2021

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.