Quinoxaline and its derivatives have been studied extensively for their relevant biological activity and transition metal selectivity. These compounds are commonly used for their antimicrobial, antifungal, antiparasitic activity, and relevance in the treatment of metabolic diseases. More recently, researchers have shifted their research focus on synthetic quinoxaline derivatives. Such compounds are found in many antibiotic medicines like echinomycin and Levomycin as they inhibit gram-positive bacterial growth. Quinoxaline’s ability to inhibit gram-positive bacterial growth has been found especially in oxygen-containing compounds, yielding promising candidates to prevent cancerous tumor growth. The breadth of quinoxaline makes it a valuable tool within the research community. We report an improved methodology using microwave assisted synthesis. This method provides easy access to a wide variety of substitution patterns, in a solvent free environment with improved yields.

Microwave assisted synthesis of quinoxaline derivatives

ACS Spring 2022

The official archive and repository for all ACS Meetings & Expositions abstracts and select posters or presentations.