<i>Mycobacteria Tuberculosis</i> (TB) is an infectious disease that results in over a million deaths annually worldwide. SLU 2345 has demonstrated activity against TB and further research is necessary to characterize the binding site and investigate its mode of action on the target. This research is focused on fluorescent labelling of SLU 2345 via click chemistry and other known synthetic methods. Progress on the synthesis of the tagged analogs is currently underway.

Fluorescent labeling an analog showing activity against <i>Mycobacterium tuberculosis</i> in three steps

ACS Spring 2022

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Fluorescent labeling an analog showing activity against Mycobacterium tuberculosis in three steps