Objectives:
Muscle weakness is a common problem among severely burned intensive care patients. Rehabilitation is recommended to start immediately to minimize the risk of muscle loss, and one of the rehabilitation methods that can be considered during the early intensive care phase is motorised in-bed cycling exercise. As part of a larger study, the aim was to assess the feasibility for in-bed cycling, regarding respiratory response during exercise, in an early phase of intensive care with invasive mechanical ventilation at the Burn Center at Uppsala University Hospital, Sweden.
Methods:
10 Burn-ICU patients, > 18 years, with continuous invasive mechanical ventilation, were monitored subsequently pre, intra and post exercise with motorised in-bed cycling device. Variables monitored were respiratory rate, saturation of peripheral oxygen (SpO2), end-tidal carbon dioxide (ETCO2), arterial saturation of peripheral oxygen (SaO2), arterial partial pressure of oxygen (PaO2) and arterial partial pressure of carbon dioxide (PaCO2).
Safety limits, where the intervention would be discontinued if exceeded, were set for vital parameters before intervention.
Results:
Nine out of ten patients managed to maintain the in-bed cycling exercise for 20 minutes, as recommended for other ICU-patients. In the one patient a temporary drop in systolic blood pressure led to a premature end to the intervention. There were no clinically relevant changes in any of the analysed respiratory-related variables, between the subsequent pre, intra and post intervention phases.
Conclusion:
In-bed cycling exercise in an early phase of Burn-ICU treatment during invasive mechanical ventilation seems feasible regarding the respiratory response. Tendencies for respiratory rate to increase were seen, however not clinically significant or exceeding preset safety limits. No other impact of clinical relevance was seen. However, larger studies need to be conducted to enable generalizable results.

**Objectives:**
Muscle weakness is a common problem among severely burned intensive care patients. Rehabilitation is recommended to start immediately to minimize the risk of muscle loss, and one of the rehabilitation methods that can be considered during the early intensive care phase is motorised in-bed cycling exercise. As part of a larger study, the aim was to assess the feasibility for in-bed cycling, regarding respiratory response during exercise, in an early phase of intensive care with invasive mechanical ventilation at the Burn Center at Uppsala University Hospital, Sweden.
**Methods:**
10 Burn-ICU patients, > 18 years, with continuous invasive mechanical ventilation, were monitored subsequently pre, intra and post exercise with motorised in-bed cycling device. Variables monitored were respiratory rate, saturation of peripheral oxygen (SpO2), end-tidal carbon dioxide (ETCO2), arterial saturation of peripheral oxygen (SaO2), arterial partial pressure of oxygen (PaO2) and arterial partial pressure of carbon dioxide (PaCO2).
Safety limits, where the intervention would be discontinued if exceeded, were set for vital parameters before intervention.
**Results:**
Nine out of ten patients managed to maintain the in-bed cycling exercise for 20 minutes, as recommended for other ICU-patients. In the one patient a temporary drop in systolic blood pressure led to a premature end to the intervention. There were no clinically relevant changes in any of the analysed respiratory-related variables, between the subsequent pre, intra and post intervention phases.
**Conclusion:**
In-bed cycling exercise in an early phase of Burn-ICU treatment during invasive mechanical ventilation seems feasible regarding the respiratory response. Tendencies for respiratory rate to increase were seen, however not clinically significant or exceeding preset safety limits. No other impact of clinical relevance was seen. However, larger studies need to be conducted to enable generalizable results.

P.093 Respiratory response during early in-bed cycling for mechanically ventilated burn patients.

Dear friends and colleagues,

We will be pleased to welcome you in Turin (Italy) for the 19th European Burns Association´s Congress in 2022. Italy is honored to hold the meeting of the European Burns Association for the second time, after Verona in 1995. Turin is easily reachable from everywhere in Europe, either travelling by car, train or choosing flight connections. During the meeting, held in the renewed industrial center of the main Italian historical automotive factory (i.e. Lingotto-FIAT), we will meet international burn specialists, focusing on standards of care, progresses in burn treatment, strategies to face disaster situations, with a special attention to education of younger colleagues. However, in your spare time, you might enjoy the sweet days of Italian late summer, simply wandering in the green parks and gardens along the two rivers which cross the city, or you might decide to discover the numerous art galleries, churches, palaces, libraries, walking across elegant squares and large boulevards, passing through centuries of art and history; finally, you may choose to immerse yourself in some of the most exciting museum experiences, such as the Cinema Museum and the Turin’s Egyptian museum.

Looking forward to seeing you all in Turin for the 19th European Association´s Congress in 2022!
Maurizio Stella, Congress President, Turin Burn Centre