Background and Aims :
Guillain Barré syndrome is responsible for symmetrical flaccid paralysis and may require artificial ventilation. The objective of this study is to show the efficacy of immunoglobulin in the management of Guillain-Barré Syndrome.
Retrospective study of patients with Guillain Barré syndrome hospitalized in PICU from January 2014 to December 2016. For each patient, epidemiological, anamnestic, clinical, biological and therapeutic data were collected.
25 children were included, average age of 6 years. The clinic was preceded by an infectious syndrome for 18 patients ). At admission 23 patients were aware reflex of absent cough in 2 children , paraparesis for 11 patients and tetraplegia for 2 children with neurovegetative disorder for 4 children . %). the average duration for the ascending phase was 8 days, the average duration for the plateau phase was 8.6 days . Fifteen cases showed albuminocytological dissociation and EMG in favor of demyelination in 14 cases . All children received immunoglobulin . Nine children required ventilation, of which 5 patients (20%) were tracheotomized. The mean duration of mechanical ventilation was 36 days, the average duration of hospitalization was 18 days. The mortality in intensive care unit was 4 children.
Guillain Barre syndrome remains a formidable affection, immunoglobulins have a primordial place in the treatment. Prognosis depends on the early diagnosis and rapid specific management.