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Jun 22, 2018

MASCC/ISOO Annual Meeting on Supportive Care in Cancer

02 / IS THERE A NEED TO RE-INTERPRET THE SCIENCE OF PROGNOSTICATION IN CANCER PAIN – RESULTS AND ANALYSIS OF AN OBSERVATIONAL TRIAL IN ADVANCED CANCER

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Arora, R.D.

ecs cp

pain prognostication

Abstract

Abstract

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Keywords

ecs cp

pain prognostication

Abstract

Is there a need to re-interpret the science of prognostication in pain – Results and analysis of an observational trial in advanced cancer Background The Edmonton Classification System for Cancer Pain (ECS-CP) has been developed for the characterization of Pain. The number of days to achieve stable pain control has been used as a surrogate measure for the complexity of pain control. Complex pain syndromes usually require a longer time period to achieve stable pain control. An essential element of the science of prognostication is the component of survival which needs to be included in the ECS CP. Neutrophil Lymphocyte ratio (NLR) and Platelet Lymphocyte ratio (PLR) have been associated with poor prognosis in advanced cancer. Objectives This paper provides a mean to combine these haematological indices as a marker of survival within the existent framework of ECS-CP. Methods The recording of baseline pain was done at the initial visit by ECS-CP. Acute exacerbation of Pain (AEP) was recorded using the Alberta breakthrough pain assessment tool (ABPAT). A Patient self record of number of AEP in a day, opioid induced adverse effects and regularity in taking medication was maintained. The minimum number of follow up visits planned (3) were not completed which prompted a rethink on the idea of prognostication. Results A weak positive correlation was obtained between NLR, PLR and Pain intensity. Conclusion A composite measure for prognostication of Pain which consists of the following components, pain assessment tools (ECS-CP, ABPAT), biochemical parameters (serum creatinine) and haematological parameters (NLR, PLR) needs to be developed.

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© Copyright 2019 Morressier GmbH.
All rights reserved.