Purpose: to investigate the association between coronary artery stenosis and survival outcomes in patients successfully resuscitated from cardiac arrest
Materials and methods: This multi-center retrospective cohort study enrolled 266 cardiac arrest survivors who received emergent coronary angiography (CAG) from the period of 2011-2017. The patients were categorized into “survival group” and “non-survival group” based on survival to hospital discharge or not. The severity of coronary artery stenosis were evaluated and compared between these two groups.
Results: There were 167 patients in the survival group and 99 patients in the non-survival group. Among the enrolled patients, there were 194 patients (73%) had at least 1-vessel coronary artery severe stenosis (≥70% stenosis), with 108 patients in survival group and 86 patients in non-survival group (65% v.s. 87%, p < 0.001). The number of coronary artery with severe stenosis was significantly lower in the survival group than in the non-survival group (1.1±1.0 v.s. 2.0±1.1, p < 0.001), and was significantly associated with survival to discharge after multiple logistic regression analysis. The increase number of coronary artery with severe stenosis contributed to a higher risk of in-hospital mortality as compared to those without severe coronary artery stenosis (1-vessel: adjusted OR 1.98, 95% CI 0.81–4.85, p = 0.13; 2-vessel: adjusted OR 4.67, 95% CI 1.79–12.17, p = 0.002; 3-vessel: adjusted OR 10.49, 95% CI 3.96–27.77, p < 0.001).
Conclusions: The increased number of coronary artery with severe stenosis is associated with in-hospital mortality after successfully resuscitation from cardiac arrest.