Antioxidant activity has been relevant in the last years due to their capacity to prevent chronical and degenerative diseases such as cancer, Parkinson, Alzheimer among others. However the obtention of metabolites from plants becomes difficult since their content varies depending on the season. In this regard, microbial metabolites can offer a variety of compounds regardless of the season, specially those coming from actinobacteria; where an adequate extraction depending on the polarity can be useful in determining the nature of compounds with antioxidant activity and therefore perform afterwards biotechnological processes to increase their production. In this research secondary metabolites of Gordonia sp. were extracted in increasing order of polarity (hexane, isopropilic eter, ethyl acetate and methanol), such extracts were screened with chemical tests to demonstrate the presence of carbohydrates, terpenes, flavonoids, among others, and in order to identify the extract that presented more compounds with antioxidant activity, a DPPH-TLC was performed. Metabolites such as tanins, flavonoids, carbohydrates, proteins and alcaloids were found on the less polar extracts while in the more polar extracts (ethyl acetate and methanol) were found coumarins, alcoloids and monosaccharides. With the DPPH-TLC technique it was found that the hexane extract was the one that presented more metabolites with antioxidant activity. Further analysis need to be done to deepen the research

Caracterización preliminar de la actividad antioxidante de metabolitos hidrofílicos e hidrofóbicos de Gordonia sp. por DPPH-CCF

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