AIMS: This study aimed to assess the proposed outcome measures to use in the MACRO trial and identify any redundant outcome measures. METHODOLOGY: Seventy patients with CRS underwent these proposed outcome measures: •Objective: Peak Nasal Inspiratory Flow (PNIF), Peak Expiratory Flow, Saccharin test •Subjective: Sniffin’ sticks test (TDI score), SNOT-22 Pearson’s correlations between SNOT-22 scores and outcome measurements were calculated. Interviews explored participants’ feedback. RESULTS: There was a significant negative correlation between SNOT-22 “Blockage” and PNIF. There was no significant correlation between SNOT-22 “Smell” rating and TDI scores; SNOT-22 “Runny” rating and Saccharin test. The interviews revealed the outcome measures were acceptable and valued by participants. CONCLUSION: The Sniffin’ Sticks test remains a valuable outcome measure. Although PNIF correlated with self-rating scores, it remains a simple cheap test to perform and valued by participants. The saccharin test was not valued by participants and has been removed from the trial measures.
No datasets are available for this submission.
No license information is available for this submission.