We use cookies to ensure that we give you the best experience on our website Learn more

Home

Saved research

Submission

Deep venous thrombosis in burn patients: a retrospective analysis

Submitted

13 Views
0 Downloads
0 Saves

Presentation

thumbnail

Abstract

Deep venous thrombosis in burn patients: a retrospective analysis Fierens J, Hoste E, Benoit D, Monstrey S, Colpaert K OBJECTIVE: Deep venous thrombosis (DVT) is a well-known cause of major morbidity in the surgical patient population. The objective of this retrospective study is to evaluate the incidence of DVT in our burn centre, identify burn-related risk factors as well as risk factors for bacterial surinfection of DVT. METHODS: All adult burn patients, with a total body surface area (TBSA) more than 10%, diagnosed with DVT and admitted between 2008 and 2016 in our burn centre were retrospectively evaluated. The analysis included demographics, location of central lines, number of surgeries, pre-existing medical conditions and inhalation injury. All patients received either routine weight-adjusted subcutaneous low-molecular weight heparin (LMWH) prophylaxis or intravenous heparin. A continuous heparin infusion with a targeted activated partial thromboplastin time (aPTT) of 1.5 to 2 times the baseline aPTT or enoxaparin 0.5 mg/kg was considered an adequate prophylactic dose of anticoagulant. DVT patients were matched on age, gender and TBSA with our general burn unit population. RESULTS: During the study period 611 patients were admitted to the burn unit. 27 patients were diagnosed with DVT (4.4%). The average length of stay in the DVT group was 56 days, compared to 27 days in the control group (P < 0.01). No increased mortality was found (P= 0.34). Pre-existing medical conditions, inhalation trauma nor blood transfusion were associated with a higher incidence of DVT (P > 0.05). DVT was associated with a sub therapeutic daily dose of LMWH, adjusted for length of stay or time to diagnosis (P < 0.05). A total of 11 (41%) patients had surinfected DVT, with either bacteria (6/11, 54%) or yeasts (5/11; 46%). In all patients a central line was located on the DVT location, with a more frequent femoral site (18/27, 67%). CONCLUSION: This study stresses the importance of routine and correctly dosed LMWH administration in burn patients. It highlights the presence of a central line as a major risk factor and the additional hazard of thrombus surinfection.

Datasets

No datasets are available for this submission.

License

No license information is available for this submission.

Morressier

Company

Legal

Follow us

© Copyright 2020 Morressier GmbH. All rights reserved.

Morressier

© Copyright 2020 Morressier GmbH.
All rights reserved.