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May 11, 2018

Europe Stroke Organisation Conference

DIFFUSION-WEIGHTED ASPECTS AS A FUNCTIONAL OUTCOME PREDICTOR IN PATIENTS WITH ACUTE ISCHEMIC STROKE TREATED WITH ENDOVASCULAR THERAPY UP TO 24 HOURS

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Ciardi, C.;

Cirio, J.J.;

Buezas, M.D.;

Vila, J.F.;

Caballero, M.L.;

Lopez, M.A.;

Chudyk Huberuk, J.P.;

Maida, G.;

Lylyk, P.

acute ischemic stroke

diffusion-weighted aspects

endovascular treatment

Abstract

Abstract

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Keywords

acute ischemic stroke

diffusion-weighted aspects

endovascular treatment

Abstract

Introduction In acute ischemic stroke patients Diffusion-weighted ASPECTS is correlated with infarct volume and also is an independent factor of functional outcome. Objetive Our aim is to assess the impact of pre-treatment Diffusion-weighted ASPECTS on outcomes after endovascular treatment (EVT) within 24 hs. Materials and Methods Patients aged 18-80 years ago with acute ischemic stroke with large vessel occlusion from anterior circulation eligible for EVT within 24 hours were included in this descriptive, monocentric, ambispective study. Vascular neurologists and neurorradiologist measured ASPECTS on DWI according to the method by Barber et al. Diffusion-weighted ASPECTS were grouped in ≥ 6 (Group A) or < 6 (Group B) The primary outcome measured was a modified Rankin scale (mRs) ≤ 2 at 90 days. Secondary outcomes included a successful reperfusion, defined as a modified Thrombolysis in Cerebral Infarction (mTICI) scale 2b/3, mortality rate at 90 days and symptomatic intracranial hemorrhage (SIH). Results We included 83 patients, 56 in Group A and 27 in Group B. Demographics data, risk factors, SIH and successful reperfusion did not show significant differences. The rate of mRS ≤ 2 at 90 days was 69,6% in Group A as compared with 29.6% in Group B (P=0.0006 OR=5.4 IC=1.9-14.8), the rate of mortality was 3,6% Group A while in Group B was 19% (P=0,022 OR=0.16 IC=0.02-0.90). Conclusion Diffusion-weighted ASPECTS ≥ 6 seems to be a good parameter predicting favorable outcome among patients treated by EVT within 24 hs.

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All rights reserved.