Background /Aims: interdental papilla loss has been a major problem faced daily by periodontists and restorative dentists, as the demand of achieving better esthetics and better function of teeth and periodontium has recently increased. This study aims to assess the efficacy of hyaluronic acid to be an effective treatment for interdental papilla loss in the esthetic zone and study the factors associated with reconstruction. Materials and methods: 38 patients were referred for treatment to the Periodontology post graduate clinics of Jordan University of Science and Technology for treatment of IDP loss. At the beginning 27 subjects (17 females and 10 males) from those referred, were included. A total of 21 patients included in the analyses (14 females and 7 males), of which 86 interdental sites (58 sites in the upper jaw and 28 sites in the lower jaw) treated and followed up. 0.2ml of HYADENT BG was injected in each receded IDP site and injections were repeated after 21 days, follow up was at 3 and 6 months. The height of the interdental papilla was evaluated preoperatively and postoperatively after 3 and 6 month recall using photographs and UNC probe. Papilla sites were evaluated and statistically analyzed, satisfaction and pain were assessed, and any side effects experienced by the patients were recorded. Results: A significant gain in papillary height was noticed for all recall appointments (p<0.05). The change was noticed more in the females 0.8 (mm) at 3 months and 0.6 (mm) at 6 months period compared to baseline (P<0.05), and in the upper jaw 0.9 (mm) decrease at 3 months and 0.7 (mm) decrease at 6 months period compared to baseline (P<0.05). A reduction in PD was noticed but there was no statistical difference between the various recall intervals. The final results were satisfying for the patients especially females (46.9% vs. 34.4% for males (p>0.05).minimal pain was noticed, however 2 patients have reported localized blueish swelling at some sites of injections, nevertheless no systemic side effects were reported by any of the patients. Conclusion: In aesthetically relevant areas the use of HA is recommended. It can be successfully used for construction of missing interdental papillae in women with maxillary papillary loss.
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