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Feb 12, 2018

Pan Arab Rheumatology Congress

Juvenile SLE with lupus Anticoagulant and hypoprothrominemia syndrome

juvenile sle

hyporothrombinemia

lupus anticoagulant

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juvenile sle

hyporothrombinemia

lupus anticoagulant

Abstract

Juvenile SLE with lupus Anticoagulant and hypoprothrominemia syndrome Mohammed Olfat, MD1. Ahmed Tarawah, MD2. Doaa Mohammed3. Meyasser Olfat4. • ¹ Division of Rheumatology, Maternity and Children Hospital • 2 Division of Hematology, Maternity and Children Hospital • 3 Division of paediatrics, Maternity and Children Hospital • 4 Medical school, Taibah University • Corresponding Author: • Mohammed Olfat, MD • Division of Rheumatology • Maternity and Children Hospital • Prince Abdul Majeed Road • Medina, Saudi Arabia • Phone: +966-5-04356467 • Fax: +966-14-8640915 • e-mail: mmmoholfat@yahoo.com Abstract Lupus anticoagulant and hypoprothrombinemia syndrome (LAC–HPS) is a rare clinical entity that can occur in association with juvenile SLE. We described a girl with systemic lupus erythematosus who developed hemorrhagic tendencies as a consequence of a clotting factor II (prothrombin) deficiency. She responded rapidly to treatment with corticosteroids and the coadministration of vitamin K and fresh frozen plasma. The addition of cellcept has enabled the control of disease manifestations and the reduction in steroid doses.

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