Background/Aim: Mechanical thrombectomy (MT) is superior to medical management of ischaemic stroke caused by large vessel occlusion (LVO). We aim to assess the safety and efficacy of MT in patients with mild Stroke and LVO, who were largely excluded from clinical trials. Method: Patients who had a pre-stroke modified Rankin scale (mRS) ≤2 and National Institute of Heath Stroke Scale (NIHSS) ≤7 underwent MT were identified from our prospective database for patients treated with MT from May 2016 to Aug 2018. Successful recanalization was defined as modified treatment in cerebral ischaemia (mTICI) 2b/3. Favorable clinical outcome was defined as mRS 0-2 to 90 days. Results During the study period, 24 patients met the study criteria. 20 patients had an M1 occlusion, while 4 patients had a basilar artery occlusion. 18 patients had an mTICI of 2b/3 with 7 patients received thrombolysis; 15 of these patients had a favourable clinical outcome with no mortality in this group. 6 patients had an mTICI < 2b with 5 patients received thrombolysis; only 1 patient of these 6 patients had a favourable clinical outcome, with 1 patient died. There were no complications of MT procedure or symptomatic intracerebral haemorrhages in this cohort of patients. Conclusion: Our study cohort had a good recanalization rate and favourable clinical outcomes which does not appear to change with or without thrombolysis. Our data suggests that MT is safe and effective in patients presenting with a mild stroke syndrome. It may need further clinical trials to confirm this findings.
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