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METABOLIC SYNDROME AS A COMMON RISK FOR STROKE IN NORMAL WEIGHT HYPERTENSION: A MULTI-SITE SURVEY FROM 11 PRIMARY CARE SETTINGS IN THAILAND

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ESOC-2019

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Abstract

Background and Aims: Metabolic syndrome (MetS) is a multi-complex risk of stroke and cardiovascular disease. Hypertension with MetS had at least three- folds higher risk for developed stroke. Most of the previous studies examined MetS in obese, few studies in none-obese, but not in a population of hypertension. We determined the prevalence of MetS and metabolic components in normal weight (BMI < 23.0 kg/m2) hypertension. Methods: Among 1,461 hypertensions attended 11 rural health care units in southern Thailand, 571 (39%) were normal weight. Data were obtained by structure interview, medical records, and by measurements of anthropometric, blood pressure, fasting plasma glucose, and lipid profiles. MetS was defined according to NCEP-ATP III criteria. Weight circumference was defined based on NCEP-APC criteria, a cut-off points of 80 cm in women and 90 cm in men indicated abdominal obesity. Results: Prevalence of MetS was 54.8% in normal weight hypertension. Components of MetS were hypertension co-existed with hypertriglyceridemia (47.8%), HDL (47.3%), hyperglycemia (42.6%), and abdominal obesity (33.6%). All of these components were significantly attributed of MetS. Based on logistic Wald values, MetS was strongly attributed by low HDL (Wald 190.52, RR 27.99, 95%CI 17.44-44.94), hypertriglyceridemia (Wald 183.81, RR 22.41, 95%CI 14.30-35.14), abdominal obesity (Wald 70.18, RR 4.81, 95%CI 3.33- 6.95), and hyperglycemia (Wald 70.81, RR 4.81, 95%CI 3.33-6.95), respectively. Conclusions: Over a half of normal weight hypertension had MetS. Common co-existed components were low HDL, hypertriglyceridemia, and hyperglycemia. This finding warrants further research explored cardiovascular event in this patient group, and clinical practice to prevent MetS in normal weight person.

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© Copyright 2020 Morressier GmbH.
All rights reserved.