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Noninvasive cerebral Electrical Stimulation to Reduce Unilateral Spatial Neglect After stroke

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Presented at

11th World Stroke Congress

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Abstract

Background: Post-stroke unilateral spatial neglect (USN) can be caused by balance disorders of brain electrical activity in both hemispheres, predominantly in the right parietal lobe. Recent literature suggests that spatial perception could be improved by rebalancing of hemispheric activity through non-invasive brain stimulation. Objective: To evaluate the effect of Transcranial directcurrent stimulation (tDCS) on USN after stroke of the right hemisphere. Population studied and intervention: this prospective, randomized controlled double-blind trial will include individuals of both genders, aged above 18 years, with diagnosis of stroke and USN, confirmed by imaging tests and USN diagnosis by Behavior Inattention Tests. Patients with USN will be randomized into three groups: 1 - Treatment with anodic tDCS in right parietal lobe; 2 - Treatment with cathodic tDCS in left parietal lobe; 3 - Sham. Randomization of a maximum of 45 patients is planned with 15 patients in each group. Individuals will be assessed by Catherine Bergego Scale, NIHSS, Functional Independence Measure, Barthel Scale, mRs, and Quality of Life Scale by an investigator blinded to treatment the patient received before the first session and 1 week after the last tDCS session. We will use regression models considering confounding factors for statistical analysis of the data. Results: In March 2017, 32 patients were recruited, of which seven were effectively included. Our greatest difficulties were the delay in patient inclusion after a stroke, disinterest in participating in the study, difficulty in transportation to the study center, problems in the center's infrastructure and unavailability of trained personnel for patient recruitment. Conclusion: Given the importance of USN in the stroke context, the effectiveness of tDCS in stroke rehabilitation is expected to be verified at the end of the study.

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© Copyright 2020 Morressier GmbH.
All rights reserved.