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Oct 15, 2018

7th Congress of the European Academy of Paediatric Societies

PREVALENCE OF 1-YEAR CHRONIC RESPIRATORY MORBIDITY AMONG EXTREMELY PRETERM INFANTS AND RELATED HOSPITAL LENGTH OF STAY, READMISSIONS, AND HEALTHCARE COSTS: A RETROSPECTIVE CLAIMS ANALYSIS

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preterm birth

neonatology

pulmonology

Abstract

Abstract

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Keywords

preterm birth

neonatology

pulmonology

Abstract

Background and aims Chronic respiratory morbidity (CRM) is associated with extremely preterm birth. We evaluated the prevalence of CRM, and compared initial hospital length of stay (LOS), readmissions and healthcare costs for extremely preterm infants with/without CRM, through one year corrected age (CA). Methods This was a retrospective analysis of the US Truven MarketScan claims database. Included infants were born ≤28 weeks gestational age (GA) and admitted to a neonatal intensive care unit, January 2009–June 2016; survived to 36 weeks postmenstrual age; had no congenital heart disease, diaphragmatic hernia, or congenital malformations. CRM was defined as ≥1 of the following events in ≥2 quarters through 1 year CA: re-hospitalization or emergency room visit due to a respiratory cause, use of daily respiratory medication, or use of home oxygen therapy/respiratory aids. Results Overall, 1782 infants with data through 1 year CA were included in the analysis; 1265 (71.0%) had no CRM; 517 (29.0%) had CRM. Approximately 86.7% (448/517) of infants with CRM had BPD. Mean initial hospital LOS was longer for infants with CRM versus no CRM (98 vs 78 days; P<0.0001). Re-hospitalization rates were higher for infants with CRM versus no CRM, for all diagnoses (40.4% [209/517] vs 14.2% [180/1265], P <0.0001) and respiratory diagnoses (30.9 vs 6.5%, P <0.0001). Total healthcare costs were significantly higher for CRM versus no CRM infants (Table). Conclusions Nearly one third of extremely preterm infants experience CRM through 1 year CA. CRM places a significant burden on health care systems with longer LOS and increased readmissions and healthcare costs.

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© Copyright 2019 Morressier GmbH.
All rights reserved.