Type 1 diabetes mellitus is characterized by a high level of glucose in the blood, requires lifelong insulin therapy and can cause acute and chronic complications in various organs and systems, including neurocognitive dysfunction. The purpose: to study the role of the insulin therapy regimen in the development of cognitive impairment in patients with type 1 diabetes mellitus. Materials and methods: 60 patients with type 1 diabetes mellitus were examined. All patients were divided into 2 groups: the 1st group received insulin with the help of multiple injections, the 2nd group - in the regime of pump insulin therapy. All patients underwent general clinical examination, testing of cognitive functions with the Montreal scale. The statistical analysis was carried out using the software package R-system. Results: the study revealed that in both groups with type 1 diabetes mellitus the decreased cognitive function was registered. It is shown that pump insulin therapy is associated with better performance of the tasks of the Montreal scale. In addition, it has been shown that more frequent episodes of diabetic ketoacidosis and high HbA1c are the main causes of cognitive impairment in this group of patients. Conclusion: cognitive disorders associated with acute and chronic hyperglycemia were verified in patients with type 1 diabetes. Pump insulin therapy improves cognitive functions.
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