Background – Though there is high risk of stroke after transient ischemic attack(TIA)and minor stroke,urgent intervention have been shown to be associated with substantial reduction in stroke recurrence. The objective of our  study was to evaluate  early stroke recurrence at 3 months   and 1 year outcome and their predictors  in patients with TIA and minor stroke (NIHSS ≤5) who receive urgent intervention. Methods-- The study was a retrospective cohort study of  TIA/ minor stroke patients admitted within 48 hours of onset from 2011 to 2016. Results—Of the 460 patients,20.6% were females. Mean age was 59.8 years(±13.1).Risk of ischemic stroke was  8% at 3 months. Multivariate analysis showed diabetes mellitus(OR 2.1, CI 1.06-4.4, p=0.02) and > 50% vessel stenosis/occlusion (OR 3.7, CI 1.4-9.5, p= 0.01) were independent predictor of early recurrence of stroke. 23.3% and 14.4% of patients had  unfavourable outcome(mRS ≥2) at 3 months and 1 year respectively. Multivariate analysis showed that significant vessel stenosis/occlusion (OR 2.8, CI 1.1-7.1, p=0.02),presence of small vessel ischemic changes(OR 2.09, CI 1.1-4.1, p=0.02) and microbleeds (OR 2.1, CI 1.05-4.2,p=0.03) were independently associated with unfavourable functional outcome at 3 months whereas CAD(OR 2.8,CI 1.1-7.1,p=0.02), presence of white matter hyperintensity (CR 5.1, CI 1.5-17.4,p=0.01)and  microbleeds(CI 3.8,CI 1.5-9.9, p=0.01) were independently associated with poor functional outcome at 1 year. Conclusion: Though  urgent treatment after TIA and minor stroke is associated with reduced risk of early stroke recurrence, substantial portion of patients had unfavourable outcome at 3 months and 1 year.

SHORT TERM AND LONG-TERM OUTCOME AND PREDICTORS OF RECURRENCE  OF VASCULAR EVENTS FOLLOWING EARLY TREATMENT OF TRANSIENT ISCHEMIC ATTACK(TIA) AND MINOR STROKE