Introduction: General therapeutic hypothermia associates with such side effects like arterial hypotension, arrhythmias, increase of pneumonia rate. Selective craniocerebral therapeutic hypothermia is one of the superficial therapeutic hypothermia technique.
Objectives: To investigate the impact of craniocerebral therapeutic hypothermia on mean blood pressure (MBP), heart rate, incidence of intrahospital pneumonia and sinusitis.
Materials and methods
Total amount of patients was 107 acute ischemic stroke patients (hypothermia group -87 patients; control group - 20 patients). Including criteria was acute ischemic stroke first 72 hours onset; NIHSS >4 points. Excluding criteria was bradycardia, conducted trombolysis or/and thrombectomy. We used standard stroke treatment protocol in both groups, the cooling helmet device for hypothermia group during 24 h. We measured MBP, heart rate before and after first 24 h. Intrahospital pneumonia and sinusitis rate was calculated on 7th day.
Mean blood pressure before treatment was 111,7±16,8 mm Hg in hypothermia group, 119,6±23,9mm Hg; control group (p=0,08), after 24 h it was 104,2±14,9mm Hg in hypothermia group, 106,0±16,1mm Hg in control group (p= 0,63). Heart rate before treatment was 83,4±16,8` in hypothermia group, 81,0±12,97` in control group, after 24 h it was 77,6±15,2 ` in hypothermia group, 77,8±13,6 ` in control group (p>0.05). Intrahospital pneumonia rate was 13.8% in hypothermia group and 30% in control group (p=0.08). There was not any intrahospital sinusitis cases in both groups.
The therapeutic hypothermia with the use of cooling helmet does not depress on hemodynamic parameters and does not increase the number of pneumonia and sinusitis.