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Nov 12, 2017

International Diabetes Federation 2017 Congress

Turkish nationwide survey of glycemic and other metabolic parameters of patients with diabetes melitus (TEMD Study)

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Sonmez, A.;

Haymana, C.;

Bayram, F.;

Salman, S.;

Dizdar, O.S.;

Gurkan, E.;

Kargılı Carlıoglu, A.;

Kucuk Bicer, B.;

Barcin, C.;

Sabuncu, T.;

Satman, I.;

Temd Study Group, T.

Abstract

Abstract

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Keywords

Abstract

Background : Blood glucose is not the only predictor of cardiovascular outcome in diabetes. Optimization of other metabolic parameters such as lipids, arterial blood pressure (ABP), and body weight as well as a healthy lifestyle are utmost important. Aim: The primary aim of this nationwide survey was to find out the achievement of glycemic and other metabolic control parameters in Turkish adult patients with type 1 or type 2 diabetes. The secondary aim was to find out the best predictors of optimal metabolic control. Methods: Patients who were under follow-up in the same center for at least a year were registered sequentially between 01 April and 30 June 2017, in 68 tertiary endocrine units, in 37 cities. Demographic, anthropometric, clinical and biochemical data, including medications were recorded for each patient. Blood Pressures were measured by standardized electronic sphygmomanometers. Both current and former (previous 12 to 18 moths) laboratory data were recorded. Exclusion Criteria: Pregnancy, Age <18years, Decompensated liver disease, Psychiatric disorders interfering cognition or compliance, Bariatric surgery, Renal replacement therapy. Statistical analysis: Logistic regression was performed to analyze the independent determinants of current HbA1c levels. Results A total of 5240 patients with type 1(9.1%) and type 2 diabetes(90.9%) were enrolled (Table-1). Patients with type 1 diabetes had worse glycemic control than type 2 (8.69±1.97% vs. 7.73±1.75%; p<0.001). Figure-1 depicts the percentage of patients with controlled metabolic parameters and living a healthy lifestyle (HbA1c ≤7.0%, LDL-cholesterol(LDL-C) <100 mg/dl, Arterial Blood Pressures (ABP) <140/90 mmHg, Body Mass Index (BMI) between 18.5-30kg/m2, Non-smoker and performing regularly exercise (>60 min/week)). Patients who met the HbA1c, LDL-C and ABP goals: Type 1 diabetics n=28 (6.0%) Type 2 diabetics n=446 (9.6%) Patients who met the additional healthy lifestyle goals: Type 1 diabetics n=17 (3.6%) Type 2 diabetics n=190 (2.7%) The alteration of HbA1c levels in the follow up Previous Current Type 1 diabetics 8.84±2.09% 8.69±1.98% p=0.079 Type 2 diabetics 7.90±1.88% 7.71±1.73% p<0.001 The significant determinants of optimal HbA1c in patients with type 2 diabetes are given in Table-2. In type 1 diabetes, only the higher income Odds Ratio 3.039 (95%CI:1.082-8.538) is the significant determinant of optimal HbA1c. Discussion The results of the TEMD study show that very few diabetic patients living in different regions of Turkey have optimal metabolic control, despite the fact that all the enrolled patients were under follow-up in tertiary endocrine and diabetes units. In order to make a progress in the diabetes health care, better follow-up policies should be implemented to overcome the negative determinants of optimal metabolic control.

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All rights reserved.