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Feb 24, 2019

The 6th International Conference on Nutrition and Growth

VITAMIN D SUPPLEMENTATION OF CHILDREN WITH RHEUMATIC DISEASES

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vitamin d

insufficiency / deficiency

connective tissue diseases

juvenile idiopathic arthritis

children

Abstract

Abstract

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Keywords

vitamin d

insufficiency / deficiency

connective tissue diseases

juvenile idiopathic arthritis

children

Abstract

N.S. Podchernyaeva, M.I. Tikhaya, A.A. Ivina, O.V. Shpitonkova I.M. Sechenov First Moscow State Medical University, Russian Federation Background and aims: To determine supplementation level of vitamin D in children with rheumatic diseases. Material and methods: 52 children (35 girls and 17 boys), aged from 5 to 17 years (average age 11.88±0.48 years) were observed. 29 children had connective tissue diseases (CTDs) and 23 children - Juvenile idiopathic arthritis (JIA). The level of 25(OH)D in plasma was measured by chemiluminescent immunoassay method. Concentration level 21-30ng/ml was determined as insufficiency, less than 20 ng/ml as deficiency. 17 (58.6%) patients with CTDs and 16 (69.5%) JIA patients were taking vitamin D drugs (cholecalciferol 200-400 IU/day and/or alfacalcidol 0,25 μg). Results: normal vitamin D supply was only in 5 (9.5%) children, insufficiency - in 6 (11.5%), the deficit - in 41 (79%). Vitamin D supplementation in CTDs patients was more satisfactory. 25(OH)D ˂30 ng/ml was observed in 82.8% cases in CTDs patients and in 100% cases in JIA patients, the incidence of Vitamin D deficiency was 69% versus 91.3%. The average 25(OH)D level in CTDs group (20.86 ± 2.15 ng/ml) was significantly higher than in JIA group (14.98 ± 0.91 ng/ml). Conclusions: The overwhelming majority of children with JIA and CTDs have an insufficiency or deficiency of vitamin D in comparison with Russian population. Traditional therapy with complex calcium salts drugs and cholecalciferol in low doses is insufficient to achieve the optimal level of vitamin D.

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© Copyright 2019 Morressier GmbH.
All rights reserved.