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49th Annual ESDR Meeting

September 18-21, 2019 · Bordeaux, France

esdrmeeting.org

619 submissions

IL-23 Antibodies in Psoriasis – a Non-Clinical Perspective

IL-23

antibodies

psoriasis

risankizumab

Topical Sandalore® , a specific OR2AT4-stimulating odorant, ameliorates telogen effluvium: Randomized, double-blinded, placebo-controlled trial

Sandalore

Hair growth

Telogen effluvium

Bacterial infection and wound healing in an ex vivo human skin model

wound healing

bacterial infection

EMILIN-1 is important for age-related changes in elastic fibre structure

EMILIN

Elastin

structure

A NEW 3D SKIN MODEL CONTAINING AUTOLOGOUS IMMUNE CELLS RECONSTRUCTED BY TISSUE ENGINEERING

Tissue engineering

Immune cells

Study of skin microbiota impaired by skin hygiene habits

microbiote

skin

sls

skin barrier

Evaluation of pharmacological responses to subcutaneous injection of adalimumab in InflammaSkin®, a full-thickness human ex vivo skin model reproducing key features of psoriatic lesions

subcutaneous injection

anti-inflammatory

Skin fibroblast heterogeneity and plasticity are determined by the local niche

human skin

dermis

fibroblast

Melatonin regulates melanin synthesis in human melanogenic cells

melatonin

melanogenesis

tyrosinase

An in vitro model of acne hyperseborrhea and inflammation based on hiPSC derived sebocytes

acne

sebocyte

sebogenesis

inflammation

An innervated, vascularized and immunocompetent human skin model to evaluate the properties of chemical substances.

3D model

immunology

neuroscience

Skin microbiome in cutaneous T cell lymphoma by 16S and whole genome shotgun sequencing

whole genome shotgun sequencing

Distinct gene expression signatures differentiate clinical response to ustekinumab compared to adalimumab in psoriasis

psoriasis

RNASeq

Adalimumab

Ustekinumab

Functional assessment of the atopic eczema candidate gene EMSY identifies a role in skin barrier formation

Eczema

GWAS

organotypic

Three-dimensional models of human skin at single-cell resolution in health and disease

cutaneous vasculature

A prospective observational study to assess efficacy and safety of rituximab biosimilar in Italian pemphigus patients

rituximab biosimilar

pemphigus

Epidermal stem cell competition orchestrates skin organ homeostasis and aging

Stem cells

cell competition

skin aging

Biomarkers CCL17/TARC and Total IgE Do Not Predict Clinical Response to Dupilumab in Atopic Dermatitis (AD): a Post hoc Analysis of Pooled Phase 3 Data (SOLO 1 & 2)

dupilumab

atopic dermatitis

biomarkers

Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Patients With Atopic Dermatitis

atopic dermatitis

S. aureus

dupilumab

Comparison of in vivo and in vitro tests to predict the irritation potential of surfactants and cleansing formulation

Surfactant

Skin irritation

Cleanser

Preservation of human skin integrity and metabolism during 10 days in culture with NativeSkin® system

skin integrity

metabolism

human skin assay

Identification of a new gene involved in human skin pigmentation: CLEC12B

Skin pigmentation

CLEC12B

Melanogenesis

Dermal fibroblast subpopulations as a potential cell therapy for promoting scar-free wound healing and resolving scar formation

Fibroblast Heterogeneity

Fibroblast

A CRISPR-interference screen identifies PRANCR and other novel long non-coding RNAs controlling human epidermis formation

long noncoding RNA

epidermis

CRISPR screen

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