Objectives
Immunotherapy is a major breakthrough in the treatment of cancer. The basic knowledge by patients and the general public of the immune system and its role in cancer is limited. Moreover, explaining the immune system and how immunotherapy works to patients and their caregivers, is challenging because of the extreme complexity. We have developed Immuno-T, a motion comic explaining immunotherapy. A motion comic combines a digital comic with animation, sound effects, voice-over and/or a musical score.

Methods
The scenario, story board and basic character design were developed by a hematologist and executed by game developers, and further refined in small focus groups consisting of hematologists-oncologists, psychologists, study coordinators, medical students, nurses and communication managers, into the first version. This version was evaluated by 40 people of different backgrounds, including a small number of patients, and further adapted into the final version.

Results
Immuno-T explains three types of immunotherapy in an engaging, easy-to-understand way. The majority of the evaluators (94.9%) considered the motion comic a good tool to explain immunotherapy to patients, in addition to the physician consultation. Almost 40% of the evaluators felt hopeful after watching the motion comic, 30% experienced other positive emotions (happy, well-informed, strengthened).

Conclusion
Although motion comics carry important advantages (a clear and graphic presentation of complex information and a more engaging way of delivering information), they have only rarely been used in healthcare settings. 
Immuno-T, while still evolving and growing, is ready to be rolled out in real hospital settings. We are currently preparing a clinical trial to evaluate the effectiveness of information transmission using Immuno-T: does it lead to better understanding of the given treatment? Increasing patients’ knowledge of disease and treatment has a proven impact on hope, strength and empowerment, and on adherence to the treatment.

Immuno-T, a motion comic educating patients and caregivers on how immunotherapy strategies work.