Design of the Brain Attack Surveillance--Cognitive (BASIC-Cognitive) study

L. Morgenstern1.

1University of Michigan, Stroke Program, Ann Arbor, USA.

Background: Few population estimates of vascular cognitive impairment in diverse communities exist. This study seeks to determine the association of dementia and stroke in a community of Mexican Americans and non Hispanic whites in South Texas, USA.

Methods: A random sampling of housing units in Nueces County, Texas, USA, will be generated. Field Personnel will knock on selected houses and determine if someone 65 or older resides there. Those 65 and over that consent will be screened with the Montreal Cognitive Assessment (MoCA). Those with a score of 25 or less will be invited to participate in a large battery of cognitive tests known as the Harmonized Cognitive Assessment Protocol (HCAP). Caregivers will be enrolled as well to determine positives and negatives of caregiving. Subjects will be followed for two years and measures will be repeated. Caregiver needs, community resources and gaps between needs and resources will be studied. Subjects will be linked to the Brain Attack Surveillance in Corpus Christi (BASIC) project which has ascertained all stroke cases in the community since January 1, 2000. Detailed information regarding stroke history and cognitive performance will be determined.

Results: To be obtained.


Conclusions: This will be the first comprehensive, large investigation of vascular cognitive impairment in Mexican Americans and non Hispanic whites in the USA. Using the HCAP, an international neurocognitive battery, cognitive performance following stroke can be compared across populations to identify targets to reduce cognitive impairment following stroke. 
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ClinicalTrials.gov Identifier: NCT03403257

DESIGN OF THE BRAIN ATTACK SURVEILLANCE--COGNITIVE (BASIC-COGNITIVE) STUDY