Introduction: Renal transplantation has contributed to increased hope and quality of life in patients withend-stage renal disease (ESRD). Donors should have a similar general health status with no increased riskof ESRD. Literature available shows low morbidity and mortality rates. The purpose of this audit is toconduct a follow-up of living donors at our institution.

Methods: Follow-up audit in 2017 of living donors for renal transplantation from 2011 to 2014. Variables:Age, ASA, BMI, Surgical Technique, Anaesthetic Technique, Surgical and Anaesthetic Complications andfollow-up time. Evaluation of pre-operative (PO) and follow-up variables (FL): Associated pathology (AP),Haemoglobin, Urea, Creatinine (Cr mg/dL), Glomerular filtration rate (GFR ml/kg), expected GFR at thetime of FL and Pain. Statistical analysis using SPSS® V24.

Results: Approval of Risk Management, Health and Safety&Hygiene Institutional Department. Clinical dataof 82 live donors was analized. 53 met inclusion criteria. With the beginning of laparoscopic nephrectomy in 2012, we get FL of 48-72 months in 14 laparotomies and 21 laparoscopies and FL of 30-48 months in 18 laparoscopies. Mean age 53 years (min 27 - max 77); pre-donation AP: 9 arterial hypertension, 1 DM type 2, 10 Dyslipidemia, 6 Depression and 4 patients with obesity; AP de novo in FL: 5 arterial hypertension, 4 Dyslipidemia, 4 Depression and 6 readjustment of anti-depressant medication. 1 case of intraoperativehaemorrhage, without transfusion; complications in FL: 3 incisional hernias and pain in FL was 36% postlaparotomyand 10% post-laparoscopy; mean Cr of PO 0.71 ± 0.14, FL 0.97 ± 0.22. Expected GFR: 101(max 171 - min 62); TFG FL: 73 (max 116 - min 40). Statistical significant difference was observed betweenadapted GFR in PO vs FL (p<0.001). No patients had Chronic Kidney Failure (CKF) before donation andafter that 12 patients developed stage 3A and 2 patients stage 3B of CKD.

Conclusion: Living donors in renal transplantation met the clinical requirements at the time of donation.However, when assessed in 30 months FL, there is a decrease in GFR that cannot be neglected withimportant evolution to CKF. There was also an increase in the prevalence of AP with risk factor for thedevelopment of CKF. Laparoscopy seems to have contributed to the decrease of pain. The lack ofinformation regarding the FL of the donors makes it crucial to carry out further studies, to better clarify the described findings.

03 / Living Donors in Renal Transplantation: clinical follow-up