Congenital adrenal hyperplasias (CAH) are hereditary disease with recessive autosomic transmission.They are due to a deficiency of one of the five enzymes capital for the synthesis of cortisol, from cholesterol within the adrenal cortex.The 21-hydroxylase deficiency is the most frequent (90% of cases). They are characterized by a great clinical polymorphism.

The aims of our study is to describe the clinical features of CAH reported in our series, highlighting the difficulties in the management of this pathology in short and long term, describing the clinical and laboratory steps of diagnosis. 

We report 9 cases of CAH compiled to neonatal resuscitation unit care. It’s about 3 boys, 5 girls and the karyotype was not be done in one case, aged 1day to 26 days. Consanguinity was found in 3 cases. The symptoms are dominated by salt wasting syndrome. Sexual ambiguity was found in 6 cases. The hormone assays have confirmed the diagnosis by showing high levels of 17 hydroxyprogesterone in 7 cases. 
The congenital adrenal hyperplasia was associated to malformative syndrome in 7 cases. The treatment consisted of rehydration and correction of electrolyte disturbances and hormone therapy in all patients.
The immediate outcome is good in all patients, follow-up was irregular in 3 patients, 2 patients were lost to and 2 patients were followed regularly. Two cases died. 

If problems with this condition breaks are identified in developed countries
through antenatal diagnosis and by the determination of the quantity of 17-hydroxy-progesterone, in the blood of the newborn, by radioimmunoassay and neonatal screening. In our country the CAH still present problems of early diagnosis and treatment long term and also a psychological problem.

CONGENITAL ADRENAL HYPERPLASIAS, NEONATAL REVELATION