Introduction
Cardiac biomarkers are increased in cerebrovascular conditions, especially in class III/IV, C/D New York Heart Association (NYHA) and American Cardiology Association (ACA) scales. Delta criterium allows differential diagnosis between acute and chronic conditions before the appearance of ischaemic signs at electrocardiogram / echography (Fiori P. et al, 2017). The aim of our study is to assess the impact of chronic pulmonary disease with decompensated congestive heart failure (DCHF).
Materials and Methods
So far, we recruited 368 acute strokes (AS), 89 chronic cerebrovascular conditions (CCVD), 25 other neuropsychiatric diseases (OND). They underwent chest ray and/or Computerized Tomography and blood withdrawal within 24 hours.
Results
Preliminary results show significant higher levels of troponin ths (tro ths pg/ml) and N-terminal-pro-Brain Natriuretic Peptide (NT-pro-BNP pg/ml) levels in class III/IV, C/D NYHA and ACA AS and CCVD affected with chronic pulmonary heart disease with DCHF and pleural effusion (group A: AS tro ths 143,72 sd 306, p 0,0006, NT-pro-BNP 8817,25 sd 10264,68, p 0,001; CCVD tro ths 48,41 sd 38,96, p 0,06, NT-pro-BNP 3299,07 sd 4186,86, p 0,03) compared to those without pleural effusion (group B: AS tro ths 49,58 sd 77,34, NT-pro-BNP 3378,85 sd 6593,8; CCVD tro ths 31,42 sd 27,25, NT-pro-BNP 1476,46 sd 2259,94). Better outcomes were observed in the latter compared to the former.
Conclusions
A malignant circulatory profile, characterized by increased mismatch between ejection fraction and pulmonary arterial pressure, may account for resistance to treatment and negative prognosis. Non-Invasive Positive Pressure Ventilation may help in increasing oxygenation and reducing hypercapnia and risk of haemorrhagic complicances.

BLUE BLOATER PROFILE in CEREBROVASCULAR DISEASES