Introduction
The increasing incidence of antibiotic resistant organisms is a growing threat to public health and solid organ transplantation. Urinary tract infection (UTI) is the most common infection post-renal transplantation. We sought to quantify the incidence of UTI in our renal transplant recipients and establish the extent of antibiotic resistant UTIs at our transplant centre. 
Methods
Urine culture data was extracted from electronic medical records on all renal transplant recipients at a single centre from 2014-2017. Information on the organism grown and its sensitivity to antibiotics (Ampicillin, Nitrofurantoin, Tazocin, Trimethoprim, Gentamicin, Co-amoxiclav, Ciprofloxacin, Cephalexin, Amikacin, Ertapenem) was assessed.

Results

Over the 3 year study period 1404 renal transplant recipients had a urine sample sent for bacterial/fungal culture, of which 307 (21.9%) had a positive urine culture. Culture positive UTI was most common in renal transplant recipients in the first year of transplantation, with up to 38.5% of recipients developing a UTI in the first year post transplant. Out of the 862 positive urine culture specimens from the 307 renal transplant recipients, 28 different organisms were grown (bacteria and fungi). The most common bacteria grown was Escherichia coli (E.coli) (n=292 (33.8%)), followed by mixed growth (n=129 (15.0%)) then enterococcus species (n=44 (5.1%)). Antibiotic resistance data demonstrated that 233 (79%) of the E.coli grown in renal transplant recipients were resistant to at least one antibiotic. Of the E.coli UTIs in the renal transplant recipients, 180 (61.6%) were resistant to Trimethoprim and 219 (79%) were resistant to Ampicillin. Of concern, 19% of the E.coli grown were resistant to gentamicin.
Discussion.
Antibiotic resistance in UTI is common in renal transplant recipients, especially in the first year following transplantation. Further work on the impact these infections have on renal allograft function will be used to establish the morbidity associated with UTI post-transplant.

[P105] Urinary tract infection antimicrobial resistance in renal transplant recipients: A single centre experience