Introduction
The popularity of compact proton therapy systems has increased in recent years, especially among existing established radiation oncology facilities that seek proton therapy as an addition to their service. With various combination of applications available from different vendors, this study aims to evaluate the workflow feasibility to integrate Eclipse treatment planning system (TPS), Mosaiq oncology information system (OIS), and ProteusOne proton therapy system (PTS).
Materials and Methods
The beam data acquired for existing TPS commissioning were entered in Eclipse TPS (version 15.5). In addition to depth dose curves and spot fluence profiles, Eclipse TPS requires beam lateral spreader (scanning magnets) information provided by IBA. Current Eclipse TPS provides nonlinear universal proton optimizer (NUPO) algorithm and proton convolution superposition (PCS) algorithm for optimization, and is capable for robustness optimization.
Beam data validation is done by measuring absolute dose in a solid water phantom using a PPC05 parallel chamber. A prostate plan composed of two opposite lateral beams was created and imported into Mosaiq (version 2.64). The plan was delivered with IBA AdaptDeliver and dose distributions were obtained with MatriXX PT ion chamber detector array for gamma analysis.
Results
The absolute point dose measured in the solid water was 0.08CcGE (-0.04%) different comparing to the TPS calculated dose. The average gamma analysis for the prostate plan at three different depths using 3% dose and 3 mm distance-to-agreement criteria showed 95% passing rate.
Conclusion
This study demonstrated that it is possible to integrate IBA ProteusOne with Eclipse TPS and Mosaiq OIS accurately.

Feasibility study of multi-vendor integration between Eclipse, Mosaiq and ProteusOne system